Pharmacoeconomic Study Guidelines and Implementation in the Analgesic Therapeutic Class of Tangerang City Health Department Drug Formulary

Abstract

The journal details the process and content of the Drug Formulary created by the Tangerang City Health Department and discusses the pharmacoeconomic approaches used in the selection of drugs based on the Pharmacoeconomic Study Guideline. The formulary consists of 36 types of drugs and is only applicable within the regional institution. The pharmacoeconomic study was conducted using a cost-effectiveness analysis method for the proposed formulary drug list in the analgesic therapy class. The therapeutic effectiveness of each drug is expressed as a percentage, calculated by dividing the number of cases for each drug by the total number of cases in 2018. The samples analyzed were ibuprofen suppositories, paracetamol suppositories, ketoprofen suppositories, ketorolac injections, and tramadol injections. The results of the pharmacoeconomic studies on analgesic drugs indicated that ibuprofen suppositories are highly effective and cost-effective. Despite this, the Tangerang City Health Department does not currently include ibuprofen suppositories in its formulary. Instead, they have chosen ketorolac for injection. However, based on the ICER calculation, it has been determined that the procurement cost of ketorolac injection exceeds RP99.19 per case compared to tramadol injection. Only ketoprofen suppositories are deemed suitable and eligible for inclusion in the Formulary. The lack of trained personnel in pharmacoeconomic studies meant that this crucial study was not considered important. This study could help identify medications that offer superior effectiveness at lower costs, thus providing substantial cost-effectiveness.