Prescription Patterns of Antihypertensive Medications Among Prolanis Patients at the Outpatient Clinic of Ciracas District Public Health Center, East

Abstrak

Appropriate hypertension management in Chronic Disease Management Program (Prolanis) patients is crucial to control blood pressure and prevent long-term cardiovascular complications. This study aimed to evaluate the prescribing pattern of antihypertensive drugs in Prolanis patients in outpatient clinics. This descriptive observational study with a cross-sectional design analyzed prescription data from 832 hypertensive patients who met the inclusion criteria. The majority of patients were women (80.60%) with the largest age group being in the range of 41–59 years (61.10%) and  age ≥60 years (31.10%). The prescribing pattern was dominated by monotherapy at 60.5% (n = 503), which massively used Calcium Channel Blocker (CCB) in the form of Amlodipine (96.8% of total monotherapy). Two-drug combination therapy was administered to 38.5% of patients (n = 320), with CCB + ACE Inhibitor (Amlodipine + Lisinopril) regimen as the most dominant choice (83.4%). Three-drug combination therapy was very rare (1.1%), but noted a minor polypharmacy anomaly in the form of duplication of Amlodipine preparation therapy. The antihypertensive prescribing pattern in Prolanis patients was largely in line with national and international clinical guidelines through the selection of Amlodipine and the effective combination of Amlodipine-Lisinopril. However, optimization of early initiation of two-drug combination therapy for productive age and supervision of rational prescribing need to be improved to ensure patient safety. Keywords: Amlodipine, Antihypertensive, Monotherapy, Prescribing Pattern, Prolanis, Combination Therapy.